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FISH to normal human chromosomes by using a BAC representative of the D4 fragment (centromeric green band) and a BAC representative of the D5 fragment (telomeric green band) defines the location of a previously undescribed amplicon at 8p22–23. Cohybridization with a YAC containing the CTSB gene (red band) demonstrates the CTSB locus in relation to the D4 and D5 loci.
