FIG. 5.
Function of the pseudoknot structure in EIAV translational frameshifting. (A) Predicted pseudoknot structures of indicated EIAV mutants. The slippery sequences are boxed, and mutated nucleotides are in bold type and underlined. (B) EIAV Gag and Gag-Pol polyprotein expression in Cos-1 cells transfected with CMVuk pro− proviruses containing the indicated mutants, as described in legends for previous figures. (C) Relative translational frameshifting efficiencies of the mutants compared with the wild type, calculated as described in the legend for Fig. 2. The data are representative of duplicate experiments.