Table 2.
HP-SEC analysis showing binding of wild-type DPPIV and DPPIV mutants to ADA
| DPPIV mutant | tretention no ADA | tretention + ADA | Δ(tretention no ADA − tretention + ADA) |
| Proteins expressed in Sf9 cells | |||
| Wild-type | 8.99 | 8.54 | 0.45 |
| N85A | 9.12 | 8.51 | 0.61 |
| N92A | 9.08 | 8.60 | 0.48 |
| N150A | 8.94 | 8.52 | 0.42 |
| N219A | 9.09 | 8.50 | 0.59 |
| N229A | 8.98 | 8.49 | 0.49 |
| N281A | 8.97 | 8.49 | 0.48 |
| N321A | 9.00 | 8.49 | 0.51 |
| N520A | 9.01 | 8.50 | 0.51 |
| N685A | 8.95 | 8.48 | 0.47 |
| Proteins expressed in Hi5 cells | |||
| Wild-type | 8.85 | 8.42 | 0.43 |
| N85A | 8.89 | 8.45 | 0.44 |
| N92A | 8.87 | 8.43 | 0.44 |
| N150A | 8.83 | 8.41 | 0.42 |
| N219A | 8.90 | 8.47 | 0.43 |
| N229A | 8.85 | 8.40 | 0.45 |
| N281A | 8.87 | 8.41 | 0.46 |
| N321A | 8.91 | 8.42 | 0.49 |
| N520A | 8.86 | 8.41 | 0.45 |
| N685A | 8.79 | 8.40 | 0.39 |