Table 2.

Summary of the data on NOE restraints and calculated structures

NOE restraints	ARD1	ETD151	ETD135
Intraresidue |j − i| = 0	371.3	364.0	325.2
Sequential |j − i| = 1	182.7	213.3	169.6
Medium range 2 ≤ |j − i| ≤ 4	97.7	121.0	89.7
Long-range |j − i| > 5	195.3	230.7	139.3
Total	847	929	724
Unambiguous	806	888	694
Ambiguous	41	41	30
Quality of the calculated structures
Distance violation >0.3 Å	0	0	0
Pairwise RMS differences (Å)
all-atoms	1.90 ± 0.22	1.79 ± 0.14	2.54 ± 0.29
backbone Cα atoms	0.89 ± 0.26	0.78 ± 0.11	1.43 ± 0.25
secondary structures (Cα atoms)	0.64 ± 0.15	0.48 ± 0.08	0.79 ± 0.12
Helix (Cα atoms)	0.36 ± 0.08	0.24 ± 0.09	0.36 ± 0.10
β-sheet (Cα atoms)	0.46 ± 0.11	0.44 ± 0.09	0.69 ± 0.11
L1 loop (Cα atoms)	0.45 ± 0.14	0.64 ± 0.18	0.42 ± 0.19
T2 turn (Cα atoms)	0.42 ± 0.19	0.42 ± 0.19	1.83 ± 0.53