Figure 3.
Hippocampal melatonin receptor mRNA levels after single injections of antidepressant and cocaine. Mice (6−8 per group) were injected with vehicle (Veh), fluoxetine (Flx), desipramine (Des), clomipramine (Clom), and cocaine (Coc) 24 h prior to sample collection. Results (mean ± S.E.M.) were calculated as MT1/cyclophiline and MT2/cyclophiline mRNA ratios, and are expressed as a percentage of the corresponding vehicle-treated group. No significant differences were observed between drug- vs. vehicle-treated groups; MT1= [F (4, 30) = 0.345, P = 0.845], MT2 = [F (4, 34) = 0.502, P = 0.734].