Table 1.

β-catenin mutations detected in HCCs. Indicated is the number of the codon affected and the resulting amino acid change as well as the phenotype observed by immunohistochemistry with regard to presence of β-catenin (cytoplasmic/nuclear) and GS-expression (GS).

Patient number	Codon	Mutation	Aminoacid	β-Cat cytoplasmic	β-Cat nuclear	GS
20071/2,3,-00	33	TCT > TGT	S>C	+	+	+
30600/4-05	35	ATC>AGC	I>S	+	+	+
334/2-02 24138/E-01	36	CAT>CCT	H>P	+	+	+
14865/2-05	37	TCT>TGT	S>C	+	+	+
4836/3-05	37	TCT>TTT	S>F	+	+	+
21217-00	41	ACC>GCC	T>A	+	+	+
6700/2.3.-05	44	CCT>GCT	P>A	+	-	+
6700/2.3.-05 29923/B-03	45	TCT>CCT	S>P	+	-	+
28356/2-05	45	TCT>TTT	S>F	+	+	+