Table 4.
aHaplotype | DM (398) n*;f** | CRI (380) n*;f** | χ2 | P | O.R (95% CI) |
111 | 217 (0.545) | 173 (0.046) | 4.97 | 0.03 | 0.69 (0.49–0.96) |
211 | 56 (0.14) | 40 (0.105) | 1.65 | 0.20 | 0.73 (0.44–1.19) |
112 | 18 (0.045) | 39 (0.102) | 6.94 | 0.01 | 2.37 (1.23–4.60) |
212 | 14 (0.035) | 00 (0.00) | 6.23 | 0.01 | 0.09 (0.01–0.74) |
121 | 11 (0.027) | 38 (0.1) | b13.51 | <<0.01 | 4.08 (1.83–9.11) |
221 | 01 (0.002) | 01 (0.002) | 0.43 | 0.51 | 1.08 (0.08–17.32) |
122 | 41 (0.103) | 80 (0.21) | b12.94 | <<0.01 | 2.33 (1.46–3.73) |
222 | 39 (0.098) | 09 (0.023) | b13.50 | <<0.01 | 0.23 (0.10–0.54) |
aOrder of SNPs in the DRD2 haplotypes: -141 ins/del C – G>A (Intron 1) – T>C (Intron 7)
bSignificant after Bonferroni's correction α = 0.0063
*n = total number
**f = frequency