Figure 1. Normal Rat Lungs and Rat Lungs after Receiving High-Pressure Mechanical Ventilation at a Peak Airway Pressure of 45 cm of Water.

After 5 minutes of ventilation, focal zones of atelectasis were evident, in particular at the left lung apex. After 20 minutes of ventilation, the lungs were markedly enlarged and congested; edema fluid filled the tracheal cannula. Adapted from Dreyfuss et al.⁸ with the permission of the publisher.