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Calcium(II) and cobalt(II) induce α-synuclein annular particles. (Left) Tapping mode AFM height images of particles formed after incubation at 4°C for 1 d in the presence of calcium(II) (A–C) and cobalt(II) (D–F). (Right) Height cross-sections of α-synuclein particles. Cantilever length, 160 μm; tip frequency, 267–302 kHz; set point, 1.5 V.
