Table 2.

Thermodynamics and NMR parameters for aromatic residues in HPr, BPTI, and cytochrome c

Protein	Amino acid	Proton	Δ δ (ppm)	ΔH‡ (kJ mol−1)	ΔS‡ (J mol−1 K−1)	ΔV‡ (mL mol−1)	ΔV‡ (nm3)
HPr	Tyr6	Hδ1,δ2	0.66	87 ± 17	16 ± 3	26 ± 6	0.043 ± 0.009
(3 MPa/275 K)		Hɛ1, ɛ2	0.56	87 ± 17	16 ± 3	28 ± 6	0.046 ± 0.009
HPr	Tyr6	Hδ1,δ2	0.66	89 ± 18	15 ± 3	25 ± 6	0.041 ± 0.02
(200 MPa/298 K)		Hɛ1, ɛ2	0.56	92 ± 18	16 ± 3	27 ± 6	0.045 ± 0.02
HPr average	Tyr6			89 ± 10	16 ± 2	27 ± 3	0.044 ± 0.008
BPTI	Tyr23	Hδ1,δ2		109a,c	146a,c
(0.1 MPa/329 K)a,b,c		Hɛ1, ɛ2
(0.1 MPa/329 K)a,b,c	Tyr35	Hδ1,δ2	1.10	155a,c	284a,c	36 ± 12b,c	0.06 ± 0.02b,c
(0.1 MPa/330 K)d				139e	223e	51 ± 12d	0.084 ± 0.019d
		Hɛ1, ɛ2	0.11
(0.1 MPa/329 K)a,b,c	Phe45	Hδ1,δ2	0.65	71c	46a,c	30 ± 6b,c	0.05 ± 0.01b,c
(0.1 MPa/330 K)d		Hɛ1, ɛ2				28 ± 5d	0.046 ± 0.008d
Cytochrome cf	Tyrf	Hδ1,δ2	0.86	97	96	—
(0.1 MPa)		Hɛ1, ɛ2	1.19

^a Data from Wagner et al. (1976).

^b Data from Wagner (1980).

^c Data from Wagner (1983).

^d Data from Li et al. (1999).

^e Data from Otting et al. (1993).

^f Data from Campbell et al. (1976), tyrosine residue not assigned.