Table 2.
GCPII levels – [125I]DCIT binding (fmol/mg tissue)
| Normal | Schizophrenia | Bipolar | Depression | |
|---|---|---|---|---|
| Frontal cortex | ||||
| FC-GM | 5.6 ± 0.7 (12) | 2.7 ± 0.6 (15) | 3.5 ± 0.6 (15) | 3.7 ± 0.7 (15) |
| FC-WM | 20.1 ± 1.6 (12) | 15.6 ± 0.8 (15) | 17.0 ± 2.2 (15) | 18.5 ± 1.3 (15) |
| Hippocampus | ||||
| CA1 | 1.57 ± 0.36 (10) | 1.07 ± 0.36 (11) | 1.06 ± 0.10 (6) | 1.42 ± 0.43 (10) |
| CA2 | 2.84 ± 0.49 (9) | 1.64 ± 0.36 (9) | 4.29 ± 0.95 (6) | 3.02 ± 0.49 (7) |
| CA3 | 2.95 ± 0.64 (6) | 1.76 ± 0.24 (4) | 3.50 ± 0.27 (5) | 2.70 ± 0.61 (7) |
| CA4 | 2.49 ± 0.43 (8) | 1.07 ± 0.28 (5) | 1.67 ± 0.32 (7) | 2.07 ± 0.75 (8) |
| SL | 7.10 ± 0.47 (12) | 6.43 ± 0.70 (11) | 8.80 ± 0.57 (9) | 8.96 ± 0.55 (11) |
| EC | 3.78 ± 0.53 (8) | 1.10 ± 0.45 (6) | 3.24 ± 0.80 (6) | 2.69 ± 0.50 (7) |
Values are mean ± sem; Numbers in parentheses are the number of individuals analyzed for that region. Abbreviations are as follows: FC-GM = frontal cortex gray matter; FC-WM = frontal cortex white matter; CA1-CA4 = Cornus Amonis subfields; SL = stratum lucidum; EC = entorhinal cortex.