Table 1.
Gene | Fold changeb |
---|---|
B cell transcription factor genes | |
E2A* | −2.2 ± 0.2 |
EBF* | −3.5 ± 1.0 |
Pax-5* | −2.1 ± 0.2 |
PU.1 | −3.0 ± 0.1 |
Notch-associated genes | |
Delta (Dlk-1 like) | 2.7 ± 1.0 |
Enhancer of Split (Hes) | 2.2 ± 1.0 |
Suppressor of Hairless (RBP-L) | 1.4 ± 0.2 |
Sel 11 inhibitor of Notch | −3.0 ± 0.2 |
Data from Portis and Longnecker, 2003
Microarray experiments were performed in duplicate using CD19+ bone marrow (BM) B cells from wild-type and LMP2A transgenic mice (TgE). Average fold change in gene expression in cells from TgE versus wild-type mice is shown, along with standard deviation.
Data confirmed by RT-PCR and western blot (Portis and Longnecker, 2003).