Table 2.
Mean drug concentration (μM) causing 50% cell death (IC50) after treatment of various cell lines with the five experimental compounds.
| Cell lines | [A]1 | [B] | [C] | [D] |
|---|---|---|---|---|
| MCF-7 | 2.31 | 20.327 | 5.33 | 6.508 |
| MCF-12A | 2.424 | 160 | 25.639 | 16.58 |
| A2780 | 1.158 | 22.244 | 12.996 | 17.277 |
| A2780cis | 2.58 | 37.663 | 10 | 20 |
| HeLa | 1.407 | 63.793 | 11.476 | 12.264 |
| CoLo | 7.686 | 200 | 31.141 | 26.234 |
| Primary fibroblasts | 0.887 | 170 | 11.874 | 8.046 |
| B16 | 0.115 | 49.89 | 4.999 | 2.738 |
1 Average of 3–5 experiments.