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. Author manuscript; available in PMC: 2008 Apr 7.
Published in final edited form as: Eur J Endocrinol. 2005 Oct;153(4):551–563. doi: 10.1530/eje.1.01987

Figure 3.

Figure 3

Expression of VMAT 1 and VMAT 2 mRNA (A & B) and protein (C & D) in tumours from patients with non-syndromic phaeochromocytoma (mean±s.e.m.). Levels of expression of mRNA were determined by quantitative PCR in phaeochromocytomas from 15 patients with adrenergic tumours and 11 patients with noradrenergic tumours. Expression of VMAT 1 and VMAT 2 mRNA is shown tive to that of β-actin mRNA, as described in the Methods section. Expression of VMAT 1 and VMAT 2 protein in Western blots was determined by densitometry using NIH image 1.62 software in phaeochromocytomas from 13 patients with adrenergic tumours and eight patients with noradrenergic tumours. *Significantly (P < 0.05) higher expression in non-syndromic noradrenergic than adrenergic tumours. ***Significantly (P < 0.001) higher expression in non-syndromic noradrenergic than adrenergic tumours. Note: The difference in VMAT 1 protein expression, although significant by parametric analysis (P = 0.038), failed to reach significance by non-parametric analysis (P = 0.070).