Table 4.

Tumour diameters and catecholamine concentrations, plasma catecholamines and metanephrines and tumour catecholamine release in hereditary phaeochromocytomas

	VHL (n = 18)	MEN 2 (n = 13)
Mean tumour diameter (cm)	2.6±0.2	4.3±0.6*
Tumour catecholamines
Noradrenaline (μmol/g)	15.0±2.7	32.0±8.1*
Adrenaline (μmol/g)	0.3±0.1	27.8±6.9***
Plasma catecholamines
Noradrenaline (nmol/l)	5.8±1.1	4.8±1.3
Adrenaline (nmol/l)	0.1±0.0	1.0±0.3***
Plasma metanephrines
Normetanephrine (nmol/l)	2.4±0.4	5.6±1.9
Metanephrine (nmol/l)	0.2±0.0	3.5±1.7***
Tumour catecholamine release
(nmol/l per g tumour tissue)	0.79±0.24	0.32±0.18*
(nmol/l per mmol tumour catecholamine)	76±21	12±9***

All values are means±s.e.m.

^*P < 0.05

^**P < 0.01

^***P < 0.001.