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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Microb Pathog. 2007 Oct 11;44(3):204–214. doi: 10.1016/j.micpath.2007.09.007

Figure 1.

Figure 1

Wide-ranging levels of C3 deposition on S. pneumoniae with normal human sera from healthy adult donors. Sera samples from 22 donors were heat-inactivated and incubated at 10% concentration with strains (A) JY1119 (PspA-negative), (B) WU2 (PspA clade 2) and (C) BR93.1 (PspA clade 3) followed by incubation with baby rabbit complement as exogenous complement source. The control samples were incubated with buffer instead of heat-inactivated NHS followed by incubation with baby rabbit complement. Quantification of C3 deposition was measured by flow cytometry.