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. Author manuscript; available in PMC: 2009 Mar 15.
Published in final edited form as: Virology. 2007 Dec 4;372(2):409–420. doi: 10.1016/j.virol.2007.10.044

Fig. 5.

Fig. 5

Detection of Abs to the CD4-binding site of gp120 in sera of mice immunized with the gp120/Ab complexes. Serum Abs to the CD4bs was measured by ELISA by comparing serum reactivity to gp120 in the presence or absence of sCD4. Sera were collected after the last immunization from mice immunized with gp120 combined with mAbs to CD4bs (654-D and 559/64D), mAb to V3 (694/98D), or control mAb (1418), or no antigen (PBS). These sera were serially diluted and reacted with gp120 captured on the wells in the presence or absence of sCD4 (1 μg/ml). Means and standard deviations from duplicate wells are shown. There is no statistical significant difference between Ab reactivities in the presence versus absence of sCD4.