Table 1. Chromatid distribution in multipolar ana-telophase cells.

Segregation patterns	Observed 1	Expected: obligate disjunction	Expected: obligate nondisjunction	Expected: random distribution
Disomy in tripolar mitosis
HEK293 (chr 3, 4)
4-0-0	4	0	8	1
3-1-0	9	0	0	7
2-2-0	2	8	16	5
2-1-1	9	16	0	11
Sums	24	24	24	24
P2		<0.001	<0.001	ns
WiT49 (chr 17)
4-0-0	3	0	22	2
3-1-0	17	0	0	19
2-2-0	18	22	43	14
2-1-1	27	43	0	29
Sums	65	65	65	65
P		<0.001	<0.001	ns
SW480 (chr X ,18)
4-0-0	1	0	18	2
3-1-0	14	0	0	16
2-2-0	13	18	36	12
2-1-1	26	36	0	24
Sums	54	54	54	54
P		<0.001	<0.001	ns
Tetrasomy in tripolar mitosis
HEK293 (chr 3, 4)
8-0-0	0	0	1	0,01
7-1-0	0	0	0	0,2
6-2-0	3	0	7	0,6
6-1-1	0	0	0	0,6
5-3-0	2	0	0	1,3
4-4-0	1	1	6	0,8
4-2-2	4	6	11	4,8
4-3-1	4	7	0	6,4
5-2-1	1	0	0	3,8
3-3-2	10	11	0	6,4
Sum	25	25	25	25
P		Ns	ns	ns
WiT49 (chr 12, 17)
8-0-0	1	0	2	0,03
7-1-0	3	0	0	0,4
6-2-0	5	0	18	1,5
6-1-1	1	0	0	1,5
5-3-0	4	0	0	3,1
4-4-0	7	2	13	1,9
4-2-2	11	13	27	11,5
4-3-1	13	18	0	15,4
5-2-1	6	0	0	9,2
3-3-2	9	27	0	15,4
Sum	60	60	60	60
P		<0.001	<0.001	ns
Disomy in tetrapolar mitosis
WiT49 (chr 12,17)
4-0-0-0	1	0	3	0,2
3-1-0-0	0	0	0	2,3
2-2-0-0	5	3	9	1,7
2-1-1-0	5	6	0	6,8
1-1-1-1	1	3	0	1,1
Sum	12	12	12	12
P		Ns	ns	ns
Tetrasomy in tetrapolar mitosis
WiT49 (chr 12,17)
8-0-0-0	0	0	0,3	0,001
7-1-0-0	0	0	0	0,03
6-2-0-0	2	0	3,9	0,1
6-1-1-0	0	0	0	0,2
5-3-0-0	2	0	0	0,2
5-2-1-0	0	0	0	1,3
5-1-1-1	0	0	0	0,4
4-4-0-0	2	0,3	3	0,1
4-3-1-0	2	2,6	0	2,2
4-2-2-0	4	2	11,8	1,6
4-2-1-1	1	0	0	3,2
3-3-2-0	0	0	0	2,2
3-3-1-1	0	5,3	0	2,2
3-2-2-1	4	7,9	0	6,5
2-2-2-2	4	3,0	2	0,8
Sums	21	21	21	21
P		Ns	ns	ns

¹Observations discordant with the obligate disjunction and obligate nondisjunction models are in bold and underlined type, respectively.

²P values by the Chi-Square test.