Table 2.
Univariable and multivariable analyses of factors associated with change in CD4+ level between baseline and 6 months after HAART initiation, adjusted for baseline CD4+. ANRS Co3 Aquitaine Cohort.
| Univariable | Multivariable* | |||
|---|---|---|---|---|
| Characteristic | β | P | β | P |
| MAC exposure (vs. no exposure) | −25.5 | <0.0001 | −24.7 | <0.0001 |
| Age (for one year older) | 0.3 | 0.53 | – | – |
| Women (vs. men) | −5.8 | 0.64 | – | – |
| Intravenous Drug Users (vs. other transmission groups) | −4.5 | 0.69 | – | – |
| Naive of antiretroviral treatment (vs. experienced) | 27.7 | 0.01 | 30.5 | 0.03 |
| AIDS clinical stage (vs. other clinical stages) | 13.6 | 0.32 | – | – |
| Nadir of CD4+ count <50 cells/mm3 (vs. ≥50) | −16.6 | 0.25 | −55.8 | 0.007 |
| Baseline calendar period > 2000 (vs ≤2000) | 22.3 | 0.11 | – | – |
| Baseline HIV RNA (for 1 log copies/mL higher) | 21.2 | 0.0003 | 17.8 | 0.002 |
β
coefficient of the liner regression
MAC: Mycobacterium avium complex
*
All listed characteristics included