Table 2. Interface residues of APEX1 and pol-β (closed conformation) in the 3′ complex.

Seg	Residues in APEX1	Interface Area (percentage)	Residues in pol-β	Interface Area (percentage)
1	Leu179	0–10	Arg299	0–5
	Leu182	4–7	Leu301	0–6
	Glu183	0–5	Val303	0–14
	Gln186	0–11	Thr304	0–11
	Pro234	0–7	Gly305	2–10
	Gln235	6–10	Val306	5–15
	Gln238	0–6	Ala307	0–5
2	Arg221	2–12	Gln31	7–14
	Asn222	9–16	Ile33	4–10
	Pro223	2–5	His34	16–26
	Lys224	5–17
	Gly225	2–7
3	Asn272	0–5	Ser109	6–11
	Ser275	6–12	Arg112	0–8
	Lys276	13–17	Lys113	10–13
	Asn277	1–7

The residues assembling the majority of the interface are highlighted in bold. The columns “Seg” refers to the discrete interface segments where the listed residues are located (see Figure 3). The column “Interface Area” displays range of interface area represented by a residue during MD simulation (see Table 1).