Table 7. Interface residues of APEX1 and pol-β (open conformation) in the 5′ complex with straight DNA.

Seg	Residues in APEX1	Interface Area (percentage)	Residues in pol-β	Interface Area (percentage)
Small	Lys77	1–14	Lys331	0–5
			Asp332	5–8
			Ser334	0–6
Large	Lys125	10–17	Glu9	6–9
	Glu126	5–9	Thr10	9–13
	Gly127	1–5	Leu11	2–12
	Glu149	1–10	Gly14	0–5
	Glu150	7–14	Asp17	4–6
	Gln153	3–13	Tyr49	5–14
	Glu154	6–12	Pro50	12–22
	Val180	3–12	His51	6–15
	Arg181	4–9	Lys52	11–16
	Glu183	0–7	Lys54	5–13
	Tyr184	7–16

The residues assembling the majority of the interface are highlighted in bold. The columns “Seg” refers to the discrete interface segments where the listed residues are located. The column “Interface Area” displays range of interface area represented by a residue during MD simulation (see Table 6).