. Author manuscript; available in PMC: 2009 Mar 1.

Published in final edited form as: DNA Repair (Amst). 2008 Jan 7;7(3):431–438. doi: 10.1016/j.dnarep.2007.11.015

Table 4.

Overall impact of NER, BER, TLS defects on Me-lex toxicity and mutagenicity, based only on 12mM Me-lex treatment, relative to the parental (wild type) strain.

	Decrease (↓) in S ^(a)			Decrease (↓) or increase (↑) in MF^(b)
	wt	*rev1*	*rev3*	wt	*rev1*	*rev3*
Wild type	1	↓ 2.7	↓ 2.1	1.0	↓3.9	↓3.3
rad14	↓ 1.2	↓ 4.8	↓ 1.8	↑ 1.7	↓1.5	↓2.3
apn1 apn2	↓ 9.1	↓ 12.7	↓ 50.1	↑ 21.7	↑ 2.0	↑ 5.0
mag1	↓ 7.7	↓ 50.1	↓ 50.1	↑ 3.3	↓1.6	↑ 2.5

^(a)

fold decrease in plasmid survival due to NER, BER, or TLS defects.

^(b)

fold decrease (↓) or increase (↑) in MF due NER, BER, or TLS defects.