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. 2002 Jan 1;538(Pt 1):167–177. doi: 10.1113/jphysiol.2001.012593

Table 2.

Characteristics of the step response of renal vascular resistance

Experimental condition n Baseline (mmHg ml−1 min) Minimum (mmHg ml−1 min) Plateau (% of response) Maximum of 1st response (% of plateau) Maximum of 2nd response (% of baseline)
Control 8 0.38 ± 0.04 0.19 ± 0.02 35 ± 2 93 ± 3 119 ± 6
ACE inhibition 8 0.27 ± 0.02 0.17 ± 0.01 31 ± 4 91 ± 2 103 ± 2*
Control 8 0.29 ± 0.03 0.15 ± 0.02 45 ± 2 98 ± 2 120 ± 5
ACE inhibition + ANGII 8 0.48 ± 0.04* 0.16 ± 0.02 51 ± 4 105 ± 3 139 ± 17

Baseline refers to renal vascular resistance (RVR) before the pressure reduction. Minimum refers to RVR immediately after pressure release. Plateau refers to RVR during the plateau expressed as a percentage of the total response between baseline and minimum. Maximum of the first response refers to the maximum RVR detected 2.5–10 s after release of the RAP reduction, expressed as a percentage of the level of the plateau. Maximum of the second response refers to the maximum RVR detected 25–80 s after pressure release, expressed as a percentage of baseline. Data are mean ± s.e.m.n, number of animals.

*

P < 0.05 vs. paired control.

P < 0.05 vs. ACE inhibition alone.