Table 1.
Experimental conditions | n | Baseline (mmHg) | Before shock (mmHg) | End of shock (mmHg) | Before instillation (mmHg) | End of experiment (mmHg) |
---|---|---|---|---|---|---|
No preconditioning | ||||||
Controls – no shock | 6 | 101 ± 7 | 106 ± 7 | 100 ± 4 | 99 ± 4 | 103 ± 5 |
Controls + alveolar adrenaline | 3 | 105 ± 6 | 102 ± 6 | 108 ± 4 | 100 ± 5 | 108 ± 7 |
Haemorrhagic shock | 6 | 110 ± 5 | 108 ± 3 | 35 ± 4* | 103 ± 6 | 102 ± 9 |
Haemorrhagic shock + alveolar adrenaline | 5 | 108 ± 5 | 105 ± 6 | 36 ± 4* | 97 ± 5 | 101 ± 5 |
Stress preconditioning with heat | ||||||
Controls + alveolar adrenaline | 4 | 105 ± 5 | 108 ± 6 | 104 ± 4 | 98 ± 5 | 102 ± 12 |
Haemorrhagic shock + alveolar adrenaline | 5 | 108 ± 7 | 102 ± 4 | 37 ± 5* | 99 ± 4 | 99 ± 5 |
Stress preconditioning with geldanamycin | ||||||
Controls + alveolar adrenaline | 4 | 114 ± 5 | 97 ± 4 | 106 ± 3 | 100 ± 3 | 101 ± 4 |
Haemorrhagic shock + alveolar adrenaline | 4 | 114 ± 8 | 103 ± 8 | 36 ± 2* | 102 ± 5 | 107 ± 5 |
Data are given as means ± s.e.m.
P < 0.05 vs. baseline.