Table 2.

Effect of preconditioning either with heat or geldanamycin on changes in arterial pH and calculated base deficit in control and haemorrhaged rats

		Baseline		End of haemorrhagic shock		End of experiment
Experimental conditions	n	pH	BE	pH	BE	pH	BE
No preconditioning
Controls – no shock	6	7.41 ± 0.02	1.1 ± 0.6	7.39 ± 0.02	0.9 ± 0.7	7.38 ± 0.01	1.8 ± 0.8
Controls + alveolar adrenaline	3	7.42 ± 0.03	0.5 ± 0.3	7.41 ± 0.03	1.0 ± 0.4	7.39 ± 0.02	2.0 ± 1.0
Haemorrhagic shock	6	7.44 ± 0.02	1.2 ± 0.6	7.24 ± 0.01*	−13.3 ± 1.0*	7.39 ± 0.05	2.4 ± 1.3
Haemorrhagic shock + alveolar adrenaline	5	7.41 ± 0.02	1.0 ± 0.5	7.25 ± 0.02*	−12.3 ± 1.2*	7.40 ± 0.03	2.0 ± 1.2
Stress preconditioning with heat
Controls + alveolar adrenaline	4	7.43 ± 0.02	0.5 ± 0.8	7.40 ± 0.03	0.7 ± 0.7	7.39 ± 0.02	0.5 ± 1.4
Haemorrhagic shock + alveolar adrenaline	5	7.42 ± 0.04	0.6 ± 0.5	7.26 ± 0.02*	−12.0 ± 1.4*	7.40 ± 0.02	1.3 ± 0.8
Stress preconditioning with geldanamycin
Controls + alveolar adrenaline	4	7.41 ± 0.01	0.8 ± 0.5	7.41 ± 0.04	0.9 ± 0.4	7.38 ± 0.02	1.3 ± 1.1
Haemorrhagic shock + alveolar adrenaline	4	7.43 ± 0.02	0.7 ± 0.5	7.23 ± 0.04*	−13.2 ± 1.2*	7.40 ± 0.02	1.3 ± 1.1

Data are given as means ± s.e.m.

^*P < 0.05 vs. controls. BE, base excess.