Block diagrams displaying left (filled bars) and right (open bars) ventricular volume changes with respect to time during the 12 studied time points through the cardiac cycle obtained from the normal control group (A), and rats diabetic from 13 (B), 10 (C) and 7 weeks (D), and the captopril-treated diabetic group (E) (disease durations 3, 6, 9 and 9 weeks, respectively). Each bar represents the average dV/dt ± s.e.m. between two consecutive time points through the cardiac cycle. Negative dV/dts represent contraction of the cardiac walls during systole and positive dV/dts represent their relaxation. The first bar represents dV/dt between the 1st and 2nd studied time points during the cardiac cycle with the first point timed typically 8 ms after the trigger pulse from the electrocardiographic R wave and 21 ms for the second point. The remaining bars represent dV/dts between volume points successively obtained 21, 34, 47, 60, 73, 86, 99, 112, 125, 138 and 151 ms following the R wave.