Table 2.

Diastolic and systolic volumes of the left (LV) and right ventricles (RV) of the control and the three diabetic groups spared captopril treatment normalized to their corresponding body weights

		Diabetic
	Control	3 week	6 week	9 week	P
LV end-diastolic volume/body weight (μl g−1)	1.41 ± 0.01c, d	1.38 ± 0.003c, d	1.26 ± 0.02a, b, d	1.22 ± 0.01a, b, c	<0.001
RV end-diastolic volume/body weight (μl g−1)	1.35 ± 0.01d	1.33 ± 0.01d	1.28 ± 0.02d	1.16 ± 0.02,a, b, c	<0.001
LV end-systolic volume/body weight (μl g−1)	0.5 ± 0.02c, d	0.53 ± 0.01c, d	0.64 ± 0.01a, b, d	0.71 ± 0.02a, b, c	<0.001
RV end-systolic volume/body weight (μl g−1)	0.49 ± 0.02c, d	0.51 ± 0.01c, d	0.62 ± 0.01a, b, d	0.69 ± 0.01a, b, c	<0.001
LV stroke volume/body weight (μl g−1)	0.91 ± 0.02c, d	0.85 ± 0.01c, d	0.63 ± 0.01a, b, d	0.51 ± 0.02a, b, c	<0.001
RV stroke volume/body weight (μl g−1)	0.85 ± 0.03c, d	0.81 ± 0.003c, d	0.66 ± 0.02a, b, d	0.47 ± 0.03a, b, c	<0.001

The body weight-normalized diastolic and systolic volumes of the left and right ventricles of the experimental rats were calculated using their corresponding body weights determined while they were under anaesthesia. All values expressed as means ± s.e.m.; n = 4. One-way ANOVA was used in comparison of the control and the three untreated diabetic groups followed by Tukey's Honestly Significant Difference test for pair-wise multiple comparisons. A value of P <0.05 was considered statistically significant.

^aSignificantly different from the control group.

^bSignificantly different from the 3-week diabetic group.

^cSignificantly different from the 6-week diabetic group.

^dSignificantly different from the 9-week untreated diabetic group.