Table 3.

Indices for the kinetics of left (LV) and right ventricular (RV) contraction and relaxation of the control and the three diabetic groups spared captopril treatment

		Diabetic
	Control	3 week	6 week	9 week	P
LV 25% SV and DFV (μl)	79.4 ± 1.2b, c, d	70.9 ± 1.9 a, c, d	42.9 ± 0.9a, b, d	28.6 ± 1.5a, b, c	< 0.001
RV 25% SV and DFV (μl)	74.6 ± 0.6b, c, d	67.9 ± 1.6a, c, d	44.6 ± 0.8a, b, d	26.2 ± 2.1a, b, c	< 0.001
LV time for 25% SV (ms)	14.0 ± 0.8c, d	13.8 ± 1.6c, d	34.3 ± 2.7a, b	37.3 ± 0.9a, b	< 0.001
RV time for 25% SV (ms)	14.0 ± 0.4c, d	14.0 ± 1.0c, d	34.8 ± 2.5a, b	40.3 ± 0.8a, b	< 0.001
LV time for 25% DFV (ms)	11.3 ± 0.5	11.3 ± 0.6	12.8 ± 1.1	11.8 ± 1.0	0.578
RV time for 25% DFV (ms)	10.5 ± 0.6	10.3 ± 0.5	11.5 ± 0.9	11.5 ± 1.0	0.544
LV rate of ejection during early systole (μl ms−1)	5.7 ± 0.3c, d	5.3 ± 0.5c, d	1.3 ± 0.1a, b	0.8 ± 0.03a, b	< 0.001
RV rate of ejection during early systole (μl ms−1)	5.3 ± 0.2c, d	4.9 ± 0.3c, d	1.3 ± 0.1a, b	0.6 ± 0.05a, b	< 0.001
LV rate of filling during early diastole (μl ms−1)	7.1 ± 0.4c, d	6.4 ± 0.5c, d	3.4 ± 0.3a, b	2.5 ± 0.2a, b	< 0.001
RV rate of filling during early diastole (μl ms−1)	7.2 ± 0.4c, d	6.7 ± 0.5c, d	3.9 ± 0.2a, b	2.4 ± 0.3a, b	< 0.001

All values expressed as means ± s.e.m.; n = 4. One-way ANOVA was used in comparison of the control and the three untreated diabetic groups followed by Tukey's Honestly Significant Difference test for pair-wise multiple comparisons. A value of P < 0.05 was considered statistically significant.

^aSignificantly different from the control group.

^bSignificantly different from the 3-week diabetic group.

^cSignificantly different from the 6-week diabetic group.

^dSignificantly different from the 9-week untreated diabetic group.