. 2002 Jan 15;538(Pt 2):555–572. doi: 10.1113/jphysiol.2001.012857

Table 4.

Basic physiological and MRI-derived parameters of the captopril-treated group

	Left ventricle		Right ventricle

	Value	P	Value	P
End-diastolic volume (EDV) (μl)	346.3 ± 19.5^*^†	<0.001	322.5 ± 15.1^*^†	<0.001
End-systolic volume (ESV) (μl)	132.5 ± 9.7^*	0.015	123.8 ± 5.5^*^†	0.004
Stroke volume (SV) (μl)	213.8 ± 10.1^*^†	<0.001	198.8 ± 10.5^*^†	<0.001
Ejection fraction (EF) (%)	61.8 ± 0.8^†	<0.001	61.6 ± 0.8^†	<0.001
End-diastolic volume (EDV)/body weight (μl g⁻¹)	1.4 ± 0.06^†	0.005	1.3 ± 0.02^†	<0.001
End-systolic volume (ESV)/body weight (μl g⁻¹)	0.54 ± 0.02^†	<0.001	0.50 ± 0.01^†	<0.001
Stroke volume (SV)/body weight (μl g⁻¹)	0.87 ± 0.04^†	<0.001	0.80 ± 0.01^†	<0.001
25% SV and DFV (μl)	53.44 ± 2.5^*^†	< 0.001	49.7 ± 2.6^*^†	<0.001
Time for 25% SV (ms)	14.9 ± 0.9^†	<0.001	15.8 ± 1.0^†	<0.001
Time for 25% DFV (ms)	12.9 ± 0.7	0.075	11.9 ± 0.6	0.184
Rate of ejection during early systole (μl ms⁻¹)	3.7 ± 0.3^*^†	<0.001	3.2 ± 0.2^*^†	<0.001
Rate of filling during early diastole (μl ms⁻¹)	4.2 ± 0.1^*^†	<0.001	4.2 ± 0.4^*^†	<0.001

All values expressed as means ± s.e.m. (n = 4 animals). One-way ANOVA was used in comparison of the control and the two groups made diabetic from age 7 weeks (the group spared captopril treatment and the group treated with captopril) followed by Tukey's Honestly Significant Difference test for pair-wise multiple comparisons. A value of P <0.05 was considered statistically significant.

Significantly different from the control group.

^†

Significantly different from the similarly diabetic group spared captopril treatment. The body weight-normalized values were calculated using the corresponding body weight of the anaesthetised rat.