Table 5.
Effect of butyrate and amiloride on unidirectional and net fluxes of Na+and Cl−across rabbit distal colon
| G | ISC | JNa,ms | JNa,sm | JNa,net | JCl,ms | JCl,sm | JCl,net | |
|---|---|---|---|---|---|---|---|---|
| Control | 8.8 ± 0.4 | 2.4 ± 0.1 | 4.2 ± 0.3 | 2.4 ± 0.4 | 1.8 ± 0.2 | 5.7 ± 0.4 | 6.4 ± 0.4 | −0.7 ± 0.4 |
| Butyrate | 6.9 ± 0.3§ | 0.9 ± 0.0§ | 4.3 ± 0.4n.s. | 1.4 ± 0.3* | 2.9 ± 0.3* | 4.4 ± 0.5n.s. | 4.4 ± 0.5† | 0.0 ± 0.5n.s. |
For both control (n = 9) and butyrate (n = 12) studies, values shown are means ±s.e.m. of matched tissue pairs. See Table 1 for furtherdetails and definitions.