Table 6.

Unidirectional and net fluxes of Na⁺ and Cl⁻ across rabbit distal colon pre-incubated with cholera toxin (CT)

	G	ISC	JNa,ms	JNa,sm	JNa,net	JCl,ms	JCl,sm	JCl,net
Control
Post-CT	8.2 ± 0.2	3.2 ± 0.3	4.3 ± 0.4	2.6 ± 0.3	1.7 ± 0.3	5.3 ± 0.7	9.8 ± 0.6	−4.5 ± 0.5
Post-bumetanide	8.6 ± 0.3n.s.	0.8 ± 0.1§	5.3 ± 0.4n.s.	2.8 ± 0.5n.s.	2.5 ± 0.5n.s.	8.6 ± 0.7‡	7.8 ± 0.9n.s.	0.8 ± 0.4‡
Butyrate
Post-CT	5.6 ± 0.2§	2.0 ± 0.1§	3.4 ± 0.5n.s.	0.8 ± 0.2§	2.6 ± 0.4†	5.3 ± 0.6n.s.	5.0 ± 0.6§	0.3 ± 0.5§
Post -bumetanide	5.0 ± 0.2§	0.6 ± 0.1§	4.3 ± 0.4n.s.	1.4 ± 0.2n.s.	2.9 ± 0.6n.s.	5.6 ± 1.0n.s.	4.1 ± 0.9n.s.	1.5 ± 0.4n.s.

For both control (n =7) and butyrate (n = 8), values shown are means ±s.e.m. of matched tissue pairs. Bumetanide was always added totheserosal bath solution after three flux periods. See Table 1 for further details and definitions.