Figure 6. Effect of NFA on ICl(Ca) current relaxations in response to voltage steps.
A, trace of current recorded from a single pulmonary artery myocyte. Potential was stepped from a Vh of −50 to +70 mV for 1000 ms then to −80 mV for 750 ms before returning to −50 mV. The current parameters described in Tables 1 and 2, Iinst+70, Irelax+70, Iinst-80 and Irelax-80 are shown by the arrows (see text). B, current during the voltage step protocol in the presence of NFA (100 μm). C, peak current recorded on wash out of NFA. The horizontal arrow represents zero current.