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. 2002 Mar 1;539(Pt 2):433–444. doi: 10.1113/jphysiol.2001.013322

Figure 1. PGE2 inhibits HVA ICa in Type 1 mouse trigeminal neurons.

Figure 1

A, HVA ICa elicited by stepping the membrane potential from −80 to 0 mV was inhibited by 1 μm PGE2 in a Type 1 neuron. B, a representative time plot illustrating that inhibition of HVA ICa by 1 μm PGE2 completely reversed upon washout of the drug. C, Type-1 neurons were superfused with various concentrations of PGE2 for 1 min and then washed until the current returned to pre-drug treatment amplitude. Each point represents the mean and s.e.m. of 6–12 cells.