Table 3.
Basic electrophysiological measures for the three modelled cells together with the optimal parameter values and ranges
| Cell 1 | Cell 2 | Cell 3 | ||||
|---|---|---|---|---|---|---|
| Temperature (°C) | 26 | 36 | 25 | 37 | 26 | 35 |
| Basic measures | ||||||
| Em (mV) | −65 | −65 | −64 | −68 | −69 | −71 |
| τ0 (ms) | 28.2 | 13.0 | 43.1 | 25.3 | 32.9 | 16.4 |
| Q/a0 (pC/mV) | 0.25 | 0.29 | 0.20 | 0.24 | 0.24 | 0.26 |
| RN (MΩ) | 125.8 | 55.2 | 240.8 | 128.5 | 156.5 | 79.3 |
| Derived models | ||||||
| Cm (μF cm−2) | 0.94 | 0.94 | 0.79 | 0.78 | 0.96 | 0.85 |
| (0.77−1.12) | (0.73–1.31) | (0.77–1.01) | (0.74–0.99) | (0.85–1.26) | (0.68–1.22) | |
| Ri (Ω cm) | ||||||
| Long fits | 155 | 140 | 265 | 160 | 200 | 170 |
| (73−305) | (29–375) | (180–325) | (66–265) | (155–245) | (61–240) | |
| Short fits | 110 | 110 | 250 | 40 | 200 | 170 |
| (94–230) | (38–310) | (190–285) | (18–215) | (180–225) | (140–210) | |
| Gtot(nS) | 8.3 | 18.4 | 3.8 | 7.2 | 6.0 | 11.2 |
| (7.8–9.4) | (17.7–24.1) | (3.8–4.7) | (7.0–9.2) | (5.5–7.9) | (10.1–15.8) | |
| Gsh (nS) | 1.8 | 7.3 | 3.8 | 7.0 | 3.5 | 7.7 |
| (0–4.7) | (0–11.3) | (3.4–4.0) | (6.0–7.8) | (2.7–4.2) | (6.9–9.0) | |
| Rm (kΩ cm2) | 37.4 | 21.9 | 14 200 | 998 | 90.2 | 61.9 |
| (27–94) | (11–42) | (330–450 000) | (150–400 000) | (59–150) | (40–105) | |
| Average dendritic electrotonic length (length constants, γ) | ||||||
| Apical | 0.76 | 0.95 | 0.061 | 0.18 | 0.83 | 0.93 |
| Basal | 0.29 | 0.36 | 0.023 | 0.068 | 0.26 | 0.29 |
The optimal values are shown with the range of acceptable values in parentheses underneath. For Ri, a second range of parameters is given for fits done over 2–15 ms.