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. 2002 Mar 15;539(Pt 3):725–733. doi: 10.1113/jphysiol.2001.013407

Figure 4. External ions do not affect AMPA receptor kinetics.

Figure 4

A and B, Glu responses (10 mm Glu, 1 ms duration) evoked at a range of membrane potentials (−100 to + 125 mV, 15 mV increments) in external NaCl solutions of 150 mm (A) and 55 mm (B). Responses in each ionic condition were recorded from the same patch. Unlike kainate receptors, lowering NaCl concentration did not accelerate deactivation rates but produced a modest slowing of kinetics. The junction current (1 ms) recorded at the end of the experiment with an open patch electrode is shown above each trace. C, summary of the effect of external ions on GluR-A deactivation rates in 150 mm (n = 6, •) and 55 mm (n = 5, ○) external NaCl.