Table 2.

Effect of individual injections of a NOS inhibitor and of inhibitor neurotransmitter receptor antagonists on vestibulo-ocular reflex (VOR) gain and phase lead

	VOR(0.1 Hz)		VOR(1 Hz)
Drug	ΔGain†	ΔPhase lead ‡ (deg)	ΔGain†	ΔPhase lead ‡ (deg)
l-NAME	0.06	2.7	−0.03	−3.8
	0.08*	2.7	0.03	1.6
	0.03	0.6	0.06	−1.0
	−0.01	3.1	0.03	−0.9
	0.03	0.2	0.01	1.4
Bicuculline	−0.02	1.4	−0.03	3.4
	0.01	11.2*	0.00	−0.1
	0.08*	11.0*	0.09	2.7
Strychnine	−0.10*	7.5*	−0.08	2.4
	−0.07	−0.6	0.10	−1.1
	0.10*	1.4	0.0	−0.4

^†Values represents changes in VOR gain afte drug injection. Absolute gain values in control conditions were 0.82 ± 0.04 for 0.1 Hz and 0.96 ± 0.05 for 1 Hz, n = 6.

^‡Values represent changes in VOR phase lead after drug injection. Absolute phase lead values in control conditions were 9.7 ± 1.4 for 0.1 Hz and 6.0 ± 1.1 for 1 Hz, n = 6.

^*P < 0.05 when gain ad phase leads before and after injection were compared.