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A, average I-V relationship of ICl(Ca) in absence (n = 7; •) and presence of 1 μm noradrenaline (n = 5; ○). B, typical pacemaker activity of a ICl(Ca) expressing SA node cell (Cm, 36 pF) under control conditions (▴), in the presence of 1 μm noradrenaline (•), and in the presence of both 1 μm noradrenaline and 0.2 mm DIDS (○).
