Table 2.

Effect of 0.2 mm DIDS on action potential characteristics of SA node cells expressing I_Cl(Ca) (n = 7)

	Control	DIDS
APD20 (ms)	70 ± 7	73 ± 7*
APD50 (ms)	102 ± 10	104 ± 9
APD100 (ms)	171 ± 18	172 ± 19
MDP (mV)	−60.4 ± 3.2	−60.3 ± 3.5
DDR (mV s−1)	91 ± 18	105 ± 25
Overshoot (mV)	20.9 ± 2.9	22.8 ± 3.3*
dV/dtmax (V s−1)	5.1 ± 1.5	5.1 ± 1.4
Cycle length (ms)	314 ± 38	316 ± 43

Data are means ± s.e.m.. APD₂₀, APD₅₀, and APD₁₀₀, action potention duration at 20, 50, and 100% repolarization, respectively. MDP, maximal diastolic potential; DDR, diastolic depolarization rate; Overshoot, action potential overshoot and dV/dt_max, maximum upstroke velocity.

^*P < 0.05.