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. 2002 Apr 15;540(Pt 2):543–556. doi: 10.1113/jphysiol.2001.013121

Figure 1. Various stimulation protocols used to elicit depolarizing after-potentials (DAPs).

Figure 1

A, a 750 ms step injection of 0.9 nA depolarizing current evokes a long DAP at the end of the step; B, a 3 ms 500 pA current injection elicits a single AP and a DAP lasting ∼160 ms; C, a train of 3 ms 1 nA depolarizing pulses delivered at 20 Hz to the neuron at −55 mV results in a DAP lasting > 1.5 s; D, a similar protocol as in C, to the same NGN hyperpolarized to −70 mV, results in a larger DAP. The baseline membrane potential for experiments A-C was pre-set to −55 mV. The horizontal dotted line represents the pre-set membrane potential.