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. 2002 May 15;541(Pt 1):261–271. doi: 10.1113/jphysiol.2002.016832

Figure 1. Study A: effect of reduced pre-exercise muscle glycogen on transcription of metabolic genes in reponse to 2.5 h of two-legged cycling exercise.

Figure 1

Summary data (mean ± s.e.m.) from the control (▪) and reduced glycogen (□) legs showing fold change in transcription of the pyruvate dehydrogenase kinase 4 (PDK4), uncoupling protein 3 (UCP3), hexokinase II (HKII) and lipoprotein lipase (LPL) genes (relative to β-actin) in response to 2.5 h of two-legged cycling exercise. Muscle glycogen content was reduced in one leg by one-legged cycling exercise and a low carbohydrate diet overnight. Nuclei were isolated from muscle of both the control and reduced glycogen legs before exercise (Pre), immediately after exercise (0h), and after 2 h and 5 h of recovery. Significant (P < 0.05) main effects for time were found for PDK4 and UCP3. * Significantly (P < 0.05) different from Pre in the same leg. ‡ Indicates a P value of 0.057 for PDK4 and 0.062 for HKII relative to Pre in the same leg.