Table 2.
Inhibition of rat small-intestinal SLP binding to fibronectin
| Inhibitor added (μMg) | SLP bound | ||
|---|---|---|---|
| (μg) | (ng ± s.d.) | (%) | (% inhibition) |
| None | 78 ± 8 | 87 | — |
| RGDNP (20) | 48 ± 7 | 55* | 37 |
| GPenGRGDSPA (20) | 74 ± 9 | 84 | 3 |
| Gelatin (20) | 66 ± 3 | 75** | 14 |
| Heparin (20) | 78 ± 8 | 87 | 0 |
| Chondroitin sulfate (20) | 55 ± 3 | 63** | 28 |
Wells were coated with 0.5 μg well−1 of human fibronectin, air dried, blocked with 4% bovine serum ilbumin, air dried again, and small-bowel SLP (88 ng) was added with or without inhibitors. See legend of lable 1 for further details. The amount of SLP bound was determined as described in Table 1. Student's t test I two-tailed) was used for statistical analysis.
*
P± 0.01
**
P± 0.05.