Table 1.

Properties and modulation of whole-cell outward current in olfactory bulb neurons by acute stimulation with 50 ng ml⁻¹ NGF, BDNF or NT3

Treatment	Peak current (pA)	τInact (ms)	τDeact (ms)
NGF (n = 4)
Pre	2710 ± 479	262 ± 81	3 ± 0.8
Post	2809 ± 455	330 ± 73	3 ± 0.8
BDNF (n = 7)
Pre	1612 ± 379*	230 ± 29	6 ± 2
Post	1340 ± 335	193 ± 44	7 ± 2
NT3 (n = 6)
Pre	970 ± 150	304 ± 40	11 ± 5
Post	1055 ± 95	367 ± 44	13 ± 4

τ_Inact, inactivation time constant; τ_Deact, deactivation time constant. Whole-cell outward current was evoked by a 400 ms depolarizing step from −80 to +40 mV. Values are means ± s.e.m. and n is the number of neurons sampled. Time constant values were estimated from exponential fits to the inactivating or deactivating portions of the currents. * Value after BDNF treatment (15 min) is significantly different from pretreatment value by Student's paired t test at P < 0.05.