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. 2002 Jul 15;542(Pt 2):537–547. doi: 10.1113/jphysiol.2002.018770

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The effect of noradrenaline on I_Cl(swell) in the presence of propranolol or prazosin

A, representative trace illustrating the increase of I_Cl(swell) produced by 10 μm noradrenaline in the presence of 1 μm propranolol. B, concentration-effect curve of the noradrenaline-induced increase of I_Cl(swell) at −50 mV (○) and +100 mV(•). Each point is the mean ±s.e.m. of 5 cells. C, representative trace illustrating the inhibitory effect of 3 and 10 μm noradrenaline on I_Cl(swell) in the presence of prazosin (100 nm). D, concentration-effect curve of the noradrenaline-induced inhibition of I_Cl(swell) at −50 mV (○) and +100 mV (•). The vertical axis represents the percentage of the current before noradrenaline was added. Each point is the mean ±s.e.m. of 6 cells.