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Effect of calphostin-C on ICl(swell)
A, typical cell showing the inhibition of ICl(swell) by 3 and 10 μm calphostin-C. B, leak-subtracted mean current-voltage relationship of ICl(swell) evoked by 75 mm NaCl (•) and in the same hypotonic solution containing 10 μm calphostin-C (○). Each point is the mean ±s.e.m of 5 cells. C, concentration-effect curve of the calphostin-C-induced inhibition of ICl(swell) at −50 mV (○) and +100 mV (•). Each point is the mean ±s.e.m. of 5 cells.
