Table 1.
Basal values of mean arterial pressure, heart rate, blood flow and conductance in the mesenteric and femoral beds of anaesthetized rats
MAP(mmHg) | HR(beats min−1) | Mes BF(ml min−1) | MesC(μl min−1 mmHg−1) | Fem BF(ml min−1) | FemC (μl min−1 mmHg−1) | |
---|---|---|---|---|---|---|
Control | 117 ± 3(22) | 429 ± 19(22) | 6.7 ± 0.5(22) | 57 ± 5(22) | 4.8 ± 0.2(5) | 39 ± 3(5) |
+N+I | 132 ± 3*(22) | 382 ± 11*(22) | 2.6 ± 0.2*(20) | 20 ± 6*(20) | 2.9 ± 0.3*(5) | 22 ± 2*(5) |
+Toxins | 135 ± 5*(22) | 393 ± 12(22) | 2.3 ± 0.8*(20) | 17 ± 2*(20) | 2.5 ± 0.4*(5) | 20 ± 2*(5) |
Control | 121 ± 6(5) | 404 ± 23(5) | 6.9 ± 0.7(5) | 52 ± 5(5) | ||
+Toxins | 128 ± 5(5) | 389 ± 15(5) | 6.6 ± 1.0(5) | 48 ± 6(5) | ||
+N+I | 140 ± 6(5) | 376 ± 23(5) | 3.4 ± 0.9*† (5) | 23 ± 5*† |
MAP, mean arterial pressure; HR, heart rate; BF, blood flow; C, conductance; Mes, mesenteric bed; Fem, femoral bed.
Signficantly different from control.
Significant difference between l-NAME plus indomethacin (N+I) and toxins (charybdotoxin plus apamin).