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. 2002 Aug 1;542(Pt 3):711–723. doi: 10.1113/jphysiol.2002.023341

Figure 7. Effects of ACh on ISO-stimulated ICa,l in the absence (A) and presence (B) of 10 μml-NIO.

Figure 7

A, in the absence of l-NIO, ACh elicited a prominent inhibition of ISO-stimulated ICa,l (-57 %). B, in another atrial myocyte from the same heart, l-NIO attenuated ISO-induced stimulation of ICa,l and enhanced ACh-induced inhibition of ISO-stimulated ICa,l (-78 %). C, summary of the data shows that l-NIO significantly decreased ISO-induced stimulation of ICa,l and significantly enhanced ACh-induced inhibition of ISO-stimulated ICa,l. * P < 0.05.