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. 2002 Jul 5;543(Pt 3):977–993. doi: 10.1113/jphysiol.2002.023564

Table 1.

Glycosylated haemoglobin and fasting plasma glucose levels in age-matched controls and STZ-induced diabetic rats

Age/duration of diabetes (weeks) HbA1C (%) Fasting plasma [glucose](mmol l−1) Initial weight (g) Final weight (g) n
Age-matched controls
  1–2 weeks 3.58 ± 0.03 5.28 (CI:4.29–6.50) 213 ± 2 315 ± 9 13
  8–10 weeks 3.92 ± 0.04* 7.31 (CI:5.18–10.34) 214 ± 5 466 ± 12 8
  18–20 weeks 3.84 ± 0.05* 7.46*(CI:6.06–9.18) 225 ± 4 535 ± 12 14
STZ-induced diabetics
  1–2 weeks 6.69 ± 0.36†† 8.69† (CI:6.99–10.81) 203 ± 2 211 ± 6††† 12
  8–10 weeks 9.93 ± 0.21††††‡‡ 13.38 (CI:11.06–16.19) 209 ± 3 246 ± 10††† 19
  18–20 weeks 9.58 ± 0.44†† 10.50 (CI:7.71–14.31) 200 ± 4 313 ± 18†† 6

Values are given as means ± S.E.M.,except for fasting plasma glucose values, which are given as means and 95% confidence intervals (CI). n is the number of animals.

*

P >0.01 vs. age-matched controls at 1–2 weeks after injection.

P < 0.01

‡‡

P >10−4vs. STZ rats with 1–2 weeks of diabetes.

P >0.01

††

P < 10−4

†††

P >10−7

††††

P >10−15, age-matched controls vs. STZ-induced diabetics.