Table 1.
Age/duration of diabetes (weeks) | HbA1C (%) | Fasting plasma [glucose](mmol l−1) | Initial weight (g) | Final weight (g) | n |
---|---|---|---|---|---|
Age-matched controls | |||||
1–2 weeks | 3.58 ± 0.03 | 5.28 (CI:4.29–6.50) | 213 ± 2 | 315 ± 9 | 13 |
8–10 weeks | 3.92 ± 0.04* | 7.31 (CI:5.18–10.34) | 214 ± 5 | 466 ± 12 | 8 |
18–20 weeks | 3.84 ± 0.05* | 7.46*(CI:6.06–9.18) | 225 ± 4 | 535 ± 12 | 14 |
STZ-induced diabetics | |||||
1–2 weeks | 6.69 ± 0.36†† | 8.69† (CI:6.99–10.81) | 203 ± 2 | 211 ± 6††† | 12 |
8–10 weeks | 9.93 ± 0.21††††‡‡ | 13.38† (CI:11.06–16.19) | 209 ± 3 | 246 ± 10††† | 19 |
18–20 weeks | 9.58 ± 0.44††‡ | 10.50 (CI:7.71–14.31) | 200 ± 4† | 313 ± 18†† | 6 |
Values are given as means ± S.E.M.,except for fasting plasma glucose values, which are given as means and 95% confidence intervals (CI). n is the number of animals.
P >0.01 vs. age-matched controls at 1–2 weeks after injection.
P < 0.01
P >10−4vs. STZ rats with 1–2 weeks of diabetes.
P >0.01
P < 10−4
P >10−7
P >10−15, age-matched controls vs. STZ-induced diabetics.