Table 2.
CM (n = 7) | FSM (n = 8) | SSM (n = 8) | |||||||
---|---|---|---|---|---|---|---|---|---|
1.95 | 2.10 | 2.25 | 1.95 | 2.10 | 2.25 | 1.95 | 2.10 | 2.25 | |
EC50 (μM) | 3.40 ± 0.15 | 3.10 ± 0.16 | 2.75 ± 0.16 | 2.45 ± 0.12* | 2.24 ± 0.11* | 2.03 ± 0.10* | 2.36 ± 0.13* | 2.22 ± 0.14* | 2.11 ± 0.15* |
pCa50 (μM) | 5.47 ± 0.02 | 5.51 ± 0.02 | 5.56 ± 0.03 | 5.61 ± 0.02* | 5.65 ± 0.02* | 5.70 ± 0.02* | 5.63 ± 0.03* | 5.66 ± 0.03* | 5.68 ± 0.03* |
Hill coeff. | 6.50 ± 0.29 | 6.01 ± 0.59 | 5.40 ± 0.31 | 5.63 ± 0.76 | 5.82 ± 0.30 | 5.61 ± 0.57 | 2.57 ± 0.17* | 2.39 ± 0.19* | 2.34 ± 0.21* |
CM | FSM | SSM | |||||||
ΔEC50 | 0.65 ± 0.04 | 0.42 ± 0.05* | 0.25 ± 0.04*† | ||||||
ΔpCa50 | 0.09 ± 0.01 | 0.08 ± 0.01 | 0.05 ± 0.01*† |
Each column indicates the averaged EC50, pCa50, and Hill coefficient values of the Ca2+-force curves obtained from rat cardiac trabeculae (CM), rat psoas (FSM), and soleus (SSM) muscle fibers at the SLs listed. The lower part of the table indicates the average length-dependent changes in Ca2+-sensitivity (ΔEC50 or ΔpCa50) for the three muscle types calculated as the difference in EC50 and pCa50 between SL = 2.25 μm and 1.95 μm
P < 0.01 vs.CM
P < 0.01 vs.FSM).