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. 2002 Aug 9;544(Pt 1):225–236. doi: 10.1113/jphysiol.2002.024505

Table 2.

Average values of Hill fit to Ca2+-force curves for CM, FSM and SSM muscle fibres at sarcomere lengths of 1.95, 2.10 and 2.25 μm

CM (n = 7) FSM (n = 8) SSM (n = 8)



1.95 2.10 2.25 1.95 2.10 2.25 1.95 2.10 2.25
EC50 (μM) 3.40 ± 0.15 3.10 ± 0.16 2.75 ± 0.16 2.45 ± 0.12* 2.24 ± 0.11* 2.03 ± 0.10* 2.36 ± 0.13* 2.22 ± 0.14* 2.11 ± 0.15*
pCa50 (μM) 5.47 ± 0.02 5.51 ± 0.02 5.56 ± 0.03 5.61 ± 0.02* 5.65 ± 0.02* 5.70 ± 0.02* 5.63 ± 0.03* 5.66 ± 0.03* 5.68 ± 0.03*
Hill coeff. 6.50 ± 0.29 6.01 ± 0.59 5.40 ± 0.31 5.63 ± 0.76 5.82 ± 0.30 5.61 ± 0.57 2.57 ± 0.17* 2.39 ± 0.19* 2.34 ± 0.21*
CM FSM SSM
ΔEC50 0.65 ± 0.04 0.42 ± 0.05* 0.25 ± 0.04*
ΔpCa50 0.09 ± 0.01 0.08 ± 0.01 0.05 ± 0.01*

Each column indicates the averaged EC50, pCa50, and Hill coefficient values of the Ca2+-force curves obtained from rat cardiac trabeculae (CM), rat psoas (FSM), and soleus (SSM) muscle fibers at the SLs listed. The lower part of the table indicates the average length-dependent changes in Ca2+-sensitivity (ΔEC50 or ΔpCa50) for the three muscle types calculated as the difference in EC50 and pCa50 between SL = 2.25 μm and 1.95 μm

*

P < 0.01 vs.CM

P < 0.01 vs.FSM).