Table 1.
Effects of 100 μm BAPTA/AM on Kv4.3 and Kv4.3 expressed with KChlp2d, KChlp2d-mutEF or KChlp2d-Frq
| (−)BAPTA/AM | (+)BAPTA/AM | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| τf,inact(ms) | τs,inact(ms) | Af/(Af + As) | τrec(ms) | τf,inact(ms) | τs,inact(ms) | Af/(Af + As) | τrec(ms) | n | |
| Kv4.3 | 54.4±0.9 | 425±17.6 | 0.822±0.004 | 293.9±18.4 | 49.1±1.2 | 424.1±12.1 | 0.854±0.006* | 249.6±19.0 | 5 |
| Kv4.3 + KChlp2d | 73.2±4.8 | 206.7±21.7 | 0.540±0.034 | 84.4±8.1 | 60.1±2.1 | 275.5±30.5* | 0.791±0.017 | 85.9±7.6 | 7 |
| Kv4.3 + KChlp2d-mutEF | 67.4±5.1 | 439.0±35.4 | 0.780±0.008 | 103.4±8.1 | 60.1±4.2* | 446.0±32.2 | 0.821±0.008* | 106.8±9.9 | 4 |
| Kv4.3 + KChlp2d-Frq | 54.2±3.1 | 390.3±21.8 | 0.810±0.009 | 194.9±16.2 | — | — | — | — | 12 |
Data are mean ± s.e.m. from the indicated number of oocytes. Inactivation kinetics τf,inact and τs,inact measured at +50mV. Recovery τrec measure at Vh = −100 mV. Asterisks indicate mean values that are significantly different (P < 0.01) between (−) and (+) BAPTA/AM.