Table 1.
Summary of subcellular Ca 2+ alternans characteristics
| Subcellular Ca2+ alternans | Number of cells | ARcontrol | ARmaximum | ΔARgradient |
|---|---|---|---|---|
| All forms | 29 | 0.05 ± 0.01 | 0.65 ± 0.03 | — |
| Gradients | 20 | 0.04 ± 0.01 | 0.64 ± 0.03 | 0.37 ± 0.03 |
| Out-of-phase | 12 | 0.05 ± 0.02 | 0.62 ± 0.03 | — |
| Homogeneous | 8 | 0.07 ± 0.04 | 0.68 ± 0.09 | — |
Ca2+ alternans was induced by pacing (15 cells) or by exposure to pyruvate (14 cells). AR, alternans ratio. AR control, ratio of amplitude of two successive [Ca2+]i transients before induction of alternans. ARmaximum, maximum subcellular AR. ΔARgradient, difference of the AR between the subcellular regions displaying the highest and the lowest degree of Ca2+ alternans. Data represent means ± s.e.m.